Precision or imprecision medicine?

Cardiovascular precision medicine: hope or hype?

An ever-growing number of studies and editorials herald the promise of ‘precision medicine’. On the diagnostic side, new technologies and analytical tools will allow us to pinpoint patient-specific differences and on the treatment side novel therapies will permit us to exploit those differences for better outcomes. A combination of genomic, epigenomic, transcriptomic, and metabolomics informati...

Imprecision in the Era of Precision Medicine in Non-Small Cell Lung Cancer

Over the past decade, major advances have been made in the management of advanced non-small cell lung cancer (NSCLC). There has been a particular focus on the identification and targeting of putative driver aberrations, which has propelled NSCLC to the forefront of precision medicine. Several novel molecularly targeted agents have now achieved regulatory approval, while many others are currentl...

Precision medicine, technologies, and molecular diagnostics

Introduction: Genetics, cellular and molecular medicines are cutting-edge sciences and technologies that play an important role in improving human health and quality of life. In addition, medical and biological sciences have clearly shown that the onset of diseases differs from person to person due to their different genetic profiles and variations in molecular basis. Therefore, it is feasible ...

Precision Chemistry for Precision Medicine

During the 2015 State of the Union address, President Obama unveiled plans for a $215 million Precision Medicine Initiative. The details of this plan were laid out by past and present directors of the National Institutes of Health, Harold Varmus and Francis Collins, in a commentary in the New England Journal of Medicine. While the announcement stood as a public statement of support for funding,...

Precision Medicine